KDM4A anticorps (Internal Region)

N° du produit ABIN6655514

N° du produit (Fournisseur): 600-401-x45

Cet anticorps anti-KDM4A est un anticorps Lapin Polyclonal détectant KDM4A dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour KDM4A anticorps (Internal Region) (ABIN6655514)

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KDM4A anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-x45

Fournisseur: Rockland

Fonction: JMJD2A Antibody

Réactivité croisée (Details): Cross reactivity with other species was not tested.

Purification: Anti-JMJD2a Antibody was purified by affinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-JMJD2a Antibody was produced in rabbits by repeated immunizations with a synthetic peptide from human JMJD2a containing a sequence from the internal part of the protein.

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:100 - 1:500

Western_Blot_Dilution: 1:500

Commentaires:

Anti-JMJD2a Antibody is tested for ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 121 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Agent conservateur: ProClin, Sodium azide

Précaution d'utilisation: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur KDM4A

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Autre désignation: JMJD2a

Sujet:

Synonyms: Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, JHDM3A, JMJD2, KIAA0677

Background: JMJD2a, belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Anti-JMJD2a Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics.

Gene Name: KDM4A

ID gène: 9682

NCBI Accession: NP_055478

UniProt: O75164

Pathways: L'effet Warburg